I am not endorsing these hypotheses, but they are interesting to ponder:
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Depression is neither disease nor disorder rather an adaptation that evolved to serve a purpose
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Depression is so much more prevalent than currently recognized that it is “species typical”
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Antidepressants drive neurotransmitter levels so high that homeostatic regulation kicks in
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Antidepressants may suppress symptoms in a manner that increases risk for subsequent relapse
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Cognitive therapy works by making rumination more efficient and “unsticking” self-blame
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Adding antidepressants may interfere with any enduring effect that cognitive therapy may have
Those are from a new paper by Steven D. Hollon.
